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Research Scientist: Gene Delivery
Location: Hatfield, PA 
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The research scientist is a key member of the Discovery Research Team and participates in the development of Code’s gene delivery platforms. S/he will be critical in the work we are doing to develop cell and molecular assays and to assess potency and durability of genetic payloads.  S/he will be a key contributor to the team in research, design and execution of approaches to deliver gene editing payloads to both in vitro and in vivo.

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Responsibilities

  • Work independently and a part of an interdisciplinary team to evaluate non-viral gene therapies using our patented DNA scaffold technology.

  • Develop cell and molecular assays to assess potency and durability of genetic payloads.

  • Perform in vitro assays of gene expression including ELISA, microscopy, luciferase, SEAP, and other cell-based potency assays.

  • Research, design, and execute approaches to deliver gene editing payloads to diverse cell types in vitro and in vivo.

  • Collaborate and manage projects between industry, academia, and internal partners.

  • Design and test protocols for transfer to the Development team.

  • Maintain data acquisition and analysis in electronic laboratory notebook.

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Education and Experience 

  • PhD in genetics, molecular biology, biochemistry or cell biology with 0-3 years of experience or a  BS or MS with 5+ years of laboratory experience

  • Detail-oriented with strong organizational and communication skills

  • Ability to work independently and multitask in a highly entrepreneurial environment

  • Hands-on experience with mammalian cell culture

  • Transfection and transduction in cells

  • Experience with standard molecular techniques: DNA/RNA isolation, quantitative PCR, Western blotting, fluorescence microscopy

  • Experience with various plate-based assay screens (i.e., fluorescence, luminescence, and/or ELISA)

  • Experience in molecular cloning and designing expression vectors

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Skills, Abilities and Competencies

  • Experience with non-viral vectors, AAV, and/or vaccine development

  • Experience with gene editing field and techniques such as CRISPR

  • Ability to design, coordinate, and interpret animal studies

  • Flexible and comfortable with a fast-paced and evolving business environment

  • Ability to work in parallel on multiple projects

  • Excellent communication skills

  • Self -motivated and independent minded

  • Positive interpersonal skills with the ability to interact with individuals from a variety of levels and functions

  • Responsive, can-do attitude

  • Ability to quickly adapt to rapidly changing environment and demands

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We offer a competitive salary and benefit package, including an employer matched 401k. Code Bio  is proud to be an Equal Opportunity Employer.

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Interested individuals should send a cover letter and CV to careers@codebiotx.com or:

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